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MYP_128271
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Basic Information
Hirudomacin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
61 amino acids
C288H457N89O90S8
Standard
Sequence
TPSCYEDWSRCTPGTQFLTGILWKDCNSRCKELGRRGGRCVDSPSKSCPGVLKNNKQCQCY
Physicochemical Analysis
6862.77 Da
8.89
4.32
4.00
0.0708
-0.83
0.85
-0.22
63.31
41.48
0.0820
13980.00
14480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2933.14
-38.12
111.0
103.0
224.0
475.0
11.0
66.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0041234 VERIFIED: YES
Provenance & Taxonomy
Hirudo nipponica Whitman [Animal]
Macin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella Typhimurium ATCC 14028
100 μg/mL
MBC
PMID30794960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794960/
RECORD: Rec_0198182 VERIFIED: YES
Provenance & Taxonomy
Hirudo nipponica Whitman [Animal]
Macin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
6.25 μg/mL
MBC
PMID30794960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794960/
RECORD: Rec_0273917 VERIFIED: YES
Provenance & Taxonomy
Hirudo nipponica Whitman [Animal]
Macin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
100 μg/mL
MBC
PMID30794960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794960/
RECORD: Rec_0274205 VERIFIED: YES
Provenance & Taxonomy
Hirudo nipponica Whitman [Animal]
Macin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
0.39 μg/mL
MBC
PMID30794960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794960/
RECORD: Rec_0321302 VERIFIED: YES
Provenance & Taxonomy
Hirudo nipponica Whitman [Animal]
Macin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
1.56 μg/mL
MBC
PMID30794960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30794960/
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