Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitor APER

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC19H33N7O7

DescriptionStandard

        APER
    

Molecular Weight471.51 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.39

Charge Density (pH 7.0) -0.0503

GRAVY Index-1.95

Hydrophobic Moment 0.64

Boman Index-0.63

Instability Index99.10

Aliphatic Index 25.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 241.03

LogP -2.49

H-bond Donors 8.0

H-bond Acceptors 7.0

Rotatable Bonds 13.0

Heavy Atoms 33.0

Ring Count 1.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0215694 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudocaranx sp [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity90±4 μg/mL

MethodIC50

RECORD: Rec_0323527 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity530.21

MethodIC50