‹ ›
MYP_128240
← PREVIOUS NEXT → BACK
Basic Information
Antimicrobial peptide HsAp2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
29 amino acids
C138H231N41O44S2
Standard
Sequence
SGTSEKERESERLLGVVNPLIKCFRSPCP
Physicochemical Analysis
3232.69 Da
7.78
0.45
0.20
0.0155
-0.56
0.68
-0.18
57.08
73.79
0.0345
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1382.93
-15.91
50.0
47.0
107.0
225.0
4.0
29.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0143439 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
RECORD: Rec_0144656 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
RECORD: Rec_0155203 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
RECORD: Rec_0176038 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0296631 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PMID23000095 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23000095/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 2 of 4