Peptide Database

Peptide NameInvertebrate-type lysozyme (EC 3.2.1.17) (1;4-beta-N-acetylmuramidase) (Destabilase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length136 amino acids

Chemical FormulaC657H1024N184O193S19

DescriptionStandard

        METVSVEEGLDFAPGMVSQKCLLCMCKLESGGCKPIGCRMDVGSLSCGYFQIKQPYWIDCGKPGKDWKSCSNDINCSSKCVQQYMKRYATHYRCPLNCEGFAREHNGGPNGCHSSRTLKYWELLQKIPGCKGVKFS
    

Molecular Weight15197.51 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)5.63

Net Charge (pH 7.4) 5.01

Charge Density (pH 7.0) 0.0414

GRAVY Index-0.44

Hydrophobic Moment 0.62

Boman Index-0.04

Instability Index39.04

Aliphatic Index 55.15

Aromaticity 0.0956

Extinction Coeff. Reduced 25440.00

Extinction Coeff. Oxidized 26315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6057.88

LogP -64.55

H-bond Donors 222.0

H-bond Acceptors 221.0

Rotatable Bonds 505.0

Heavy Atoms 1053.0

Ring Count 26.0

Amide Bonds 146.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0142431 VERIFIED: YES

Provenance & Taxonomy

OrganismRuditapes philippinarum [Animal]

FamilyGlycosyl hydrolase 22; Type-I lysozyme subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Anti-Gram-negative Glycosidase Hydrolase Non-hemolytic

TargetMicrococcus luteus (Gram-negative)