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MYP_128227
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Basic Information
Kunitz-type serine protease inhibitor 1 (Xb-KTI; Plants)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C96H144N24O35
Standard
Sequence
PVVDTTGNNPLQQQEEYYV
Physicochemical Analysis
2194.31 Da
4.05
-3.04
-3.10
-0.1598
-1.01
0.36
-0.06
64.56
66.32
0.1053
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
972.61
-10.89
31.0
32.0
68.0
155.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020924 VERIFIED: YES
Provenance & Taxonomy
Xanthosoma sagittifolium [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
PMID21520894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21520894/
RECORD: Rec_0046059 VERIFIED: YES
Provenance & Taxonomy
Xanthosoma sagittifolium [Plant]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella typhimurium ATCC 14028
PMID21520894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21520894/
RECORD: Rec_0079060 VERIFIED: YES
Provenance & Taxonomy
Xanthosoma sagittifolium [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
100% lysed erythrocytes (0.1% Triton X-100) and PDB (untreated control)
PMID21520894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21520894/
RECORD: Rec_0159472 VERIFIED: YES
Provenance & Taxonomy
Xanthosoma sagittifolium [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella typhimurium ATCC 14028
10 μM
MIC
PMID21520894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21520894/
RECORD: Rec_0196483 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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