MYP_128226
Basic Information
Mersacidin
Anticancer
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-positive
Immunology Innate immune defense Host defense peptide Host defense activity
Standard
20 amino acids
C81H132N20O28S4
Standard
Sequence
CTFTLPGGGGVCTLTSECIC
Physicochemical Analysis
1962.29 Da
4.05
-1.28
-1.54
-0.0638
0.94
0.21
0.39
108.01
73.00
0.0500
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
745.88
-10.22
30.0
31.0
59.0
133.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0254418 VERIFIED: NO
Provenance & Taxonomy
Bacteria [Bacterium]
Bacteriocin
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0259739 VERIFIED: YES
Provenance & Taxonomy
Bacillus sp. strain HIL Y-85 54728 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis ATCC 6633
0.78 μg/mL
MIC
RECORD: Rec_0259862 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0259979 VERIFIED: YES
Provenance & Taxonomy
Bacillus sp. strain HIL Y-85 54728 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus faecalis 21777
50.00 μg/mL
MIC
RECORD: Rec_0273315 VERIFIED: YES
Provenance & Taxonomy
Bacillus sp [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
The smallest lantibiotic known to date. Chemical modification: There are 9 post-translational modifications leading to four ring structures, residues 1-2,4-12, 13-18, and 15-20. Residues 2,4,13, and 15 are Abu. The ring structure confers chemical stability and proteolysis resistance of the peptide
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus 503
1.56 μg/mL
MIC
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