MYP_128226
Mersacidin
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Immunology
▸
Innate immune defense
▸
Host defense peptide
▸
Host defense activity
Standard
20 amino acids
C81H132N20O28S4
Standard
CTFTLPGGGGVCTLTSECIC
1962.29 Da
4.05
-1.28
-1.54
-0.0638
0.94
0.21
0.39
108.01
73.00
0.0500
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
745.88
-10.22
30.0
31.0
59.0
133.0
2.0
19.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0139862
VERIFIED: YES
Provenance & Taxonomy
Bacillus sp [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
The smallest lantibiotic known to date. Chemical modification: There are 9 post-translational modifications leading to four ring structures, residues 1-2,4-12, 13-18, and 15-20. Residues 2,4,13, and 15 are Abu. The ring structure confers chemical stability and proteolysis resistance of the peptide
Bio-Activity Profile
Antimicrobial
Bacillus subtilis ATCC 6633
0.78 μg/mL
MIC
RECORD: Rec_0142342
VERIFIED: YES
Provenance & Taxonomy
Bacillus sp [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
The smallest lantibiotic known to date. Chemical modification: There are 9 post-translational modifications leading to four ring structures, residues 1-2,4-12, 13-18, and 15-20. Residues 2,4,13, and 15 are Abu. The ring structure confers chemical stability and proteolysis resistance of the peptide
Bio-Activity Profile
Antimicrobial
S. pneumoniae A77
3.12 μg/mL
MIC
RECORD: Rec_0147717
VERIFIED: YES
Provenance & Taxonomy
Bacillus sp. strain HIL Y-85 54728 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Streptococcus pneumoniae A77
3.12
MIC
RECORD: Rec_0177328
VERIFIED: YES
Provenance & Taxonomy
Bacillus sp. strain HIL Y-85 54728 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Staphylococcus aureus 20424
3.12 μg/mL
MIC
RECORD: Rec_0187168
VERIFIED: YES
Provenance & Taxonomy
Bacillus sp [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
The smallest lantibiotic known to date. Chemical modification: There are 9 post-translational modifications leading to four ring structures, residues 1-2,4-12, 13-18, and 15-20. Residues 2,4,13, and 15 are Abu. The ring structure confers chemical stability and proteolysis resistance of the peptide
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus R85
0.78 μg/mL
MIC
Showing 5 records on this page · Page 3 of 7