Peptide Database

Peptide NameInterferon-induced transmembrane protein 3

Function Ontology

Antiviral

Antiviral ▸ Anti-Filovirus ▸ Anti-Ebola virus

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length137 amino acids

Chemical FormulaC666H1059N177O195S9

DescriptionStandard

        MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVWSLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILMVVITIVSVIIIVLNAQNLHT
    

Molecular Weight14954.19 Da

Isoelectric Point (pI)6.89

Net Charge (pH 7.0)-0.17

Net Charge (pH 7.4) -0.66

Charge Density (pH 7.0) -0.0012

GRAVY Index0.35

Hydrophobic Moment 0.49

Boman Index0.20

Instability Index26.62

Aliphatic Index 100.29

Aromaticity 0.0803

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5920.05

LogP -57.97

H-bond Donors 208.0

H-bond Acceptors 208.0

Rotatable Bonds 485.0

Heavy Atoms 1047.0

Ring Count 21.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085354 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIFITM

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser20, Ser27

Bio-Activity Profile

Function

Antiviral Entry inhibitor

TargetSARS-CoV-2

RECORD: Rec_0229454 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIFITM

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser20, Ser27

Bio-Activity Profile

Function

Antiviral Entry inhibitor Anti-EBOV

TargetEbola virus(EBOV)

RECORD: Rec_0291922 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIFITM

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser20, Ser27

Bio-Activity Profile

Function

Antiviral Entry inhibitor Replication inhibitor

TargetSARS-CoV

RECORD: Rec_0332272 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyIFITM

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser20, Ser27

Bio-Activity Profile

Function

Antiviral Anti-IAV

TargetInfluenza A virus(IAV)