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MYP_128145
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C78H133N19O22
Standard
Sequence
AVDLAKIANKVLSSLF
Physicochemical Analysis
1689.00 Da
8.63
0.80
0.60
0.0497
1.01
0.63
0.30
16.21
152.50
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
672.71
-4.94
23.0
23.0
57.0
119.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0090035 VERIFIED: YES
Provenance & Taxonomy
Rana tagoi [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
37.5 μM
MIC
PMID16675060 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16675060/
RECORD: Rec_0117713 VERIFIED: YES
Provenance & Taxonomy
Rana tagoi [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
250.0 μM
HC50
PaperA. Ohnuma et al. / General and Comparative Endocrinology 146 (2006) 242-250. Developmental and triiodothyronine-induced expression of genes encoding preprotemporins in the skin of Tago?s brown frog Rana tagoi Evidence URLhttps://www.uniprot.org/uniprotkb/Q2PGA7/entry
RECORD: Rec_0120408 VERIFIED: YES
Provenance & Taxonomy
Rana tagoi [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
150 μM
MIC
PMID16675060 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16675060/
RECORD: Rec_0145441 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 56.2%, E 0.0%, T 12.5%, C 31.2% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0161886 VERIFIED: YES
Provenance & Taxonomy
Rana tagoi [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
PaperA. Ohnuma et al. / General and Comparative Endocrinology 146 (2006) 242-250. Developmental and triiodothyronine-induced expression of genes encoding preprotemporins in the skin of Tago?s brown frog Rana tagoi Evidence URLhttps://www.uniprot.org/uniprotkb/Q2PGA7/entry
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