Peptide Database

Peptide NamePalifermin

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC729H1156N204O207S10

DescriptionStandard

        MSYDYMEGGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLAMNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIPVRGKKTKKEQKTAHFLPMAIT
    

Molecular Weight16410.87 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)8.75

Net Charge (pH 7.4) 8.27

Charge Density (pH 7.0) 0.0620

GRAVY Index-0.63

Hydrophobic Moment 0.57

Boman Index-0.11

Instability Index39.36

Aliphatic Index 69.86

Aromaticity 0.1064

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6759.33

LogP -59.94

H-bond Donors 238.0

H-bond Acceptors 229.0

Rotatable Bonds 568.0

Heavy Atoms 1150.0

Ring Count 22.0

Amide Bonds 154.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079716 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Escherichia coli [Bacterium]

FamilyGrowth factor

Tax ID9606; 562

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer

Half-Life4.5 hours (range: 3.3-5.7 hours)