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MYP_128117
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Basic Information
Thymosin beta-4
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological regulation
Standard
43 amino acids
C210H348N56O77S
Standard
Sequence
SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Physicochemical Analysis
4921.40 Da
5.02
-2.52
-2.76
-0.0587
-1.70
0.41
-0.41
61.69
40.93
0.0233
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2217.60
-25.58
72.0
76.0
179.0
344.0
4.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006297 VERIFIED: NO
Provenance & Taxonomy
Equus caballus [Animal]
Thymosin
9796
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
1:Phosphoserine; 3:N6-acetyllysine; 11:N6-acetyllysine; 22:Phosphothreonine; 25:N6-acetyllysine; 30:Phosphoserine; 31:N6-acetyllysine; 33:Phosphothreonine; 38:N6-acetyllysine
Bio-Activity Profile
-
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0044009 VERIFIED: NO
Provenance & Taxonomy
Pongo abelii [Animal]
CThymosin
9601
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
1:Phosphoserine; 3:N6-acetyllysine; 11:N6-acetyllysine; 22:Phosphothreonine; 25:N6-acetyllysine; 30:Phosphoserine; 31:N6-acetyllysine; 33:Phosphothreonine; 38:N6-acetyllysine
Bio-Activity Profile
-
the organ
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0051216 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Thymosin beta-4 (T beta-4)
9913
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
1:Phosphoserine; 3:N6-acetyllysine; 11:N6-acetyllysine; 22:Phosphothreonine; 25:N6-acetyllysine; 30:Phosphoserine; 31:N6-acetyllysine; 33:Phosphothreonine; 38:N6-acetyllysine
Bio-Activity Profile
Immunomodulatory
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Thymosin beta-4 (T beta-4) (Bos taurus): PMID 6940133 PMID6940133 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6940133/
RECORD: Rec_0053786 VERIFIED: NO
Provenance & Taxonomy
Chinchilla lanigera [Animal]
Thymosin
34839
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
1:Phosphoserine; 3:N6-acetyllysine; 11:N6-acetyllysine; 22:Phosphothreonine; 25:N6-acetyllysine; 30:Phosphoserine; 31:N6-acetyllysine; 33:Phosphothreonine; 38:N6-acetyllysine
Bio-Activity Profile
-
the organ
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0064482 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
Thymosin
9823
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
1:Phosphoserine; 3:N6-acetyllysine; 11:N6-acetyllysine; 22:Phosphothreonine; 25:N6-acetyllysine; 30:Phosphoserine; 31:N6-acetyllysine; 33:Phosphothreonine; 38:N6-acetyllysine
Bio-Activity Profile
-
the organ
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
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