Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC467H754N130O137S8

DescriptionStandard

        MVTPAVRTLTILAAILLVALQAQAEPLQARGDEVAAAPEQITADNPEVVVSLAWDESLAPKDSGSRKNMACACRIPLCLAGERRYGTCFYLGRVWAFCC
    

Molecular Weight10638.29 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0156

GRAVY Index0.31

Hydrophobic Moment 0.48

Boman Index0.12

Instability Index52.69

Aliphatic Index 99.70

Aromaticity 0.0606

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4233.37

LogP -39.83

H-bond Donors 152.0

H-bond Acceptors 144.0

Rotatable Bonds 340.0

Heavy Atoms 742.0

Ring Count 14.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311921 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence