Peptide Database

Peptide NameSLAY-screened peptide P426

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC92H134N24O31S2

DescriptionStandard

        MAGSVAYTSSFSNPCTVNHY
    

Molecular Weight2136.32 Da

Isoelectric Point (pI)6.49

Net Charge (pH 7.0)-0.42

Net Charge (pH 7.4) -0.71

Charge Density (pH 7.0) -0.0212

GRAVY Index-0.01

Hydrophobic Moment 0.21

Boman Index0.19

Instability Index54.12

Aliphatic Index 39.00

Aromaticity 0.1500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 884.13

LogP -12.63

H-bond Donors 32.0

H-bond Acceptors 34.0

Rotatable Bonds 62.0

Heavy Atoms 149.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319024 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/