Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length54 amino acids

Chemical FormulaC253H414N72O80S7

DescriptionStandard

        MRINKEMCCEAVNVLQEIQIDELDILLGGGKGHGVNTISAECRWNSLQAIFTCC
    

Molecular Weight5968.88 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-3.45

Net Charge (pH 7.4) -3.80

Charge Density (pH 7.0) -0.0638

GRAVY Index0.15

Hydrophobic Moment 0.47

Boman Index0.11

Instability Index54.54

Aliphatic Index 101.11

Aromaticity 0.0370

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2469.58

LogP -25.03

H-bond Donors 88.0

H-bond Acceptors 85.0

Rotatable Bonds 205.0

Heavy Atoms 412.0

Ring Count 4.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048316 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus mitis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria