Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC539H869N145O165S3

DescriptionStandard

        PDLTGHEKFGLGNIKYNISGIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVHISKVFVTAIFSTPLDNTGPASISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12116.73 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)2.21

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index0.09

Hydrophobic Moment 0.54

Boman Index0.15

Instability Index27.29

Aliphatic Index 98.33

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4934.17

LogP -56.16

H-bond Donors 175.0

H-bond Acceptors 173.0

Rotatable Bonds 400.0

Heavy Atoms 852.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297561 VERIFIED: NO

Provenance & Taxonomy

OrganismSapayoa aenigma [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria