MYP_128071
Buserelin
Anticancer
Hormonal / Endocrine
▸
Hormone peptide
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
XHWSYXLRP
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0245075
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Enzyme
32630
Structure & Mods
linear peptide/protein therapeutic [Linear]
noncanonical stereochemical or chemical modification [Modified]
Ambiguous/noncanonical residue symbol X present in deposited sequence
Bio-Activity Profile
Anticancer
Hormone replacement
CHO
50-80 minutes by IV dose, 80 mins. By SC dose, 1-2 hrs by Intranasal dose
RECORD: Rec_0257843
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; synthetic construct [Synthetic]
GnRH
9606;32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Hydrazide
Non-standard residues/X at 1, 6
Bio-Activity Profile
GnRH agonist
Endocrine
Anticancer
Human GnRH receptor
Clinical/Human: 4-5 h
RECORD: Rec_0311550
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
GnRH analog
32630
Structure & Mods
linear synthetic GnRH analog [Linear]
mixed L/D amino-acid peptide [Mixed]
Pyroglutamate
Ethylamide
D-Ser(tBu) at position 6
Bio-Activity Profile
Endocrine
GnRH agonist
Hormone therapy
50-80 minby IV dose, 80 min. By SC dose, 1-2 h by Intranasal dose
RECORD: Rec_0329711
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; synthetic construct [Synthetic]
GnRH
9606;32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Pyroglutamate
N-ethylamide
Non-standard residues/X at 1, 6
Bio-Activity Profile
GnRH agonist
Endocrine
Human GnRH receptor
Clinical/Human: 3.92 ± 1.01 hr