Peptide Database

Peptide NameUnnamed

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ Lipase inhibition

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Metabolic ▸ Lipid metabolism ▸ Lipid-lowering activity

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC20H28N4O6

DescriptionStandard

        PAAY
    

Molecular Weight420.46 Da

Isoelectric Point (pI)5.95

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0106

GRAVY Index0.17

Hydrophobic Moment 0.12

Boman Index0.41

Instability Index55.65

Aliphatic Index 50.00

Aromaticity 0.2500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 156.86

LogP -0.73

H-bond Donors 6.0

H-bond Acceptors 6.0

Rotatable Bonds 9.0

Heavy Atoms 30.0

Ring Count 2.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053527 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV inhibitory Antidiabetic

TargetDPP-IV

PaperExploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: an in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. Journal of Dairy Science 107:10153-10173 (2024). PMID: 39122154. PMID39122154 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/39122154/

RECORD: Rec_0425740 VERIFIED: NO