Peptide Database

Peptide NameBactridin-1 (Bact1) (Bactridine 1) (P-Arthr-Antm-beta* NaTx2.6)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC306H448N80O89S8

DescriptionStandard

        KDGYIIEHRGCKYSCFFGTNSWCNTECTLKKGSSGYCAWPACWCYGLPDNVKIFDSNNLKC
    

Molecular Weight6927.83 Da

Isoelectric Point (pI)8.17

Net Charge (pH 7.0)1.77

Net Charge (pH 7.4) 1.38

Charge Density (pH 7.0) 0.0290

GRAVY Index-0.40

Hydrophobic Moment 0.40

Boman Index0.02

Instability Index44.50

Aliphatic Index 46.39

Aromaticity 0.1639

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2730.52

LogP -27.97

H-bond Donors 103.0

H-bond Acceptors 100.0

Rotatable Bonds 220.0

Heavy Atoms 483.0

Ring Count 16.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375034 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus discrepans [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation; Cyclization

Disulfide11-61, 15-37, 23-42, 27-44

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa ATCC 27853

Activity77 μM

MethodMIC

RECORD: Rec_0375243 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus discrepans [Animal]

FamilyLong (4 C-C) scorpion toxin; Sodium channel inhibitor; Beta subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Toxin Non-hemolytic

TargetBacillus subtilis

RECORD: Rec_0409923 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus discrepans [Animal]

FamilyLong (4 C-C) scorpion toxin; Sodium channel inhibitor; Beta subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Toxin Non-hemolytic

TargetAcinetobacter calcoaceticus

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