Peptide Database

Peptide NameCathelicidin 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC799H1297N223O229S5

DescriptionStandard

        METQRASLSLGRWSLWLLLLGLALPSASAQALSYREAVLRAVDQFNERSSEANLYRLLELDPPPKEDDENPNIPKPVSFRVKETVCPRTSQQPAEQCDFKENGLVKQCVGTVTLDAVKGKINVTCEELQSVGRFKRFRKKFKKLFKKLSPVIPLLHLG
    

Molecular Weight17851.53 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)6.57

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.0416

GRAVY Index-0.36

Hydrophobic Moment 0.82

Boman Index-0.08

Instability Index37.24

Aliphatic Index 92.53

Aromaticity 0.0696

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7320.03

LogP -68.62

H-bond Donors 254.0

H-bond Acceptors 242.0

Rotatable Bonds 601.0

Heavy Atoms 1256.0

Ring Count 25.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045907 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

Familycathelicidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0201364 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]; Bos taurus [Animal]

FamilyCathelicidin

Tax ID9915; 9913

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0317129 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCathelicidin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-MRSA Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0354613 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

Familycathelicidin

Tax ID9913

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial