Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

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Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC161H273N53O47S4

DescriptionStandard

        TLQRYYCKIRRGRCAVLGCLPKEEQIGSCSVSGR
    

Molecular Weight3831.48 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)4.36

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.1282

GRAVY Index-0.37

Hydrophobic Moment 0.74

Boman Index-0.21

Instability Index68.73

Aliphatic Index 77.35

Aromaticity 0.0588

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1658.53

LogP -19.20

H-bond Donors 65.0

H-bond Acceptors 56.0

Rotatable Bonds 130.0

Heavy Atoms 265.0

Ring Count 3.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0248243 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)