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MYP_127972
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Basic Information
LSer-Def6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
34 amino acids
C154H250N52O45S6
Standard
Sequence
GTCSFSSALCVVHCRVRGYPDGYCSRKGICTCRR
Physicochemical Analysis
3742.34 Da
9.18
4.79
4.44
0.1408
-0.09
0.60
-0.13
31.68
51.47
0.0882
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1578.17
-21.16
66.0
57.0
119.0
257.0
5.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0028424 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
LSer
13632
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperAntimicrob Agents Chemother. 2015 May;59(5):2508-14 | http://www.ncbi.nlm.nih.gov/pubmed/25666157 PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0039118 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
51.6 μM
MIC
RECORD: Rec_0052045 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0063329 VERIFIED: YES
Provenance & Taxonomy
Common green [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0164471 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
100 μM
MIC
PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
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