Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC934H1405N211O277S9

DescriptionStandard

        IDHLAQVDYSLNSFPAVFQRFIDLDLKGIVYPAGNYSGPPFVAPPFTIPDQSDSMLYLAFSEYFFQSSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFMVEIQASMEAFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20309.98 Da

Isoelectric Point (pI)4.07

Net Charge (pH 7.0)-12.15

Net Charge (pH 7.4) -12.48

Charge Density (pH 7.0) -0.0664

GRAVY Index0.33

Hydrophobic Moment 0.61

Boman Index0.26

Instability Index49.19

Aliphatic Index 91.75

Aromaticity 0.1421

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7700.87

LogP -80.07

H-bond Donors 260.0

H-bond Acceptors 275.0

Rotatable Bonds 643.0

Heavy Atoms 1431.0

Ring Count 39.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403468 VERIFIED: NO

Provenance & Taxonomy

OrganismAnhinga anhinga (Anhinga) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria