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MYP_127941
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Basic Information
Magainin-2 [G13,18a], Magainin H
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
23 amino acids
C116H184N30O29S
Standard
Sequence
GIGKFLHSAKKFAKAFVAEIMNS
Physicochemical Analysis
2494.95 Da
10.00
2.85
2.59
0.1237
0.27
0.69
0.19
10.56
80.87
0.1304
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
957.13
-7.11
33.0
34.0
86.0
176.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0306912 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Magainin
8355
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
N-terminal glycine
Amidation
Bio-Activity Profile
Antimicrobial Antiparasitic Anti-Trypanosoma cruzi
Trypanosoma cruzi
500 μg/mL
Microscopy
PMID2285300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2285300/
RECORD: Rec_0312384 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus agalactiae ATCC 12386
0.25 μg/mL
MIC50
PMID3410055 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3410055/
RECORD: Rec_0313468 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
10 μg/mL
MIC50
PMID3410055 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3410055/
RECORD: Rec_0331077 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus agalactiae ATCC 12386
1 μg/mL
MIC
PMID3410055 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3410055/
RECORD: Rec_0377569 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
100 μg/mL
MIC50
PMID3410055 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3410055/
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