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MYP_127895
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Basic Information
FSEC
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
11 amino acids
C48H77N13O21S3
Standard
Sequence
CELDENNTPMC
Physicochemical Analysis
1268.39 Da
4.05
-3.25
-3.49
-0.2957
-0.83
0.13
-0.14
-5.48
35.45
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
563.84
-7.25
19.0
21.0
40.0
85.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0112112 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
SPARC
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
1-11
Bio-Activity Profile
Anti-angiogenic Anticancer
HUVEC / neuroblastoma-endothelial context
Migration assay
PaperAnti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors PMID20525313 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20525313/
RECORD: Rec_0127030 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
RECORD: Rec_0129454 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
SPARC
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
1-11
Bio-Activity Profile
Anti-angiogenic Anticancer
HUVEC / neuroblastoma-endothelial context
tube formation assay
PaperAnti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors PMID20525313 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20525313/
RECORD: Rec_0190599 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
SPARC
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
1-11
Bio-Activity Profile
Anti-angiogenic Anticancer
HUVEC / neuroblastoma-endothelial context
tumor progression assay
PaperAnti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors PMID20525313 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20525313/
RECORD: Rec_0191407 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic
PaperAntiAngioPred: A Server for Prediction of Anti-Angiogenic Peptides PMID26335203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26335203/
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