‹ ›
MYP_127873
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antiviral
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Wound healing/Regeneration ▸ Wound healing
Standard
45 amino acids
C216H377N75O59S6
Standard
Sequence
GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
Physicochemical Analysis
5161.16 Da
10.08
10.70
10.39
0.2377
-0.70
0.63
-0.36
53.13
67.11
0.0444
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2249.60
-26.02
89.0
76.0
182.0
356.0
3.0
47.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0346544 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
beta-defensin family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-40; 18-33; 23-41
Bio-Activity Profile
Antimicrobial beta-defensin family Antibacterial Host defense Defensin-like
PaperPDB 1KJ6 structural record; NMR; chain A; residues 1-45
RECORD: Rec_0354177 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Gorilla gorilla [Animal]; Macaca fascicularis [Animal]; Papio anubis [Animal]; Macaca mulatta [Animal]; Cercopithecus preussi [Animal]
Defensin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
11-40; 18-33; 23-41
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0378454 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Refer Pubmed ID 35052952: Carbapenem-resistant Klebsiella pneumoniae Bacterial isolates CRKP-1
16 μg/mL
MIC
PMID11085990;35052952 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11085990/
RECORD: Rec_0383521 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer Anti-inflammatory Wound healing
Klebsiella pneumoniae DSM681
25 μg/mL
MIC
PaperIsolation and characterization of human deta-defensin-3, a novel human inducible peptide antibiotic. PMID34521396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34521396/
RECORD: Rec_0386975 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Refer Pubmed ID 35052952: Carbapenem-resistant Klebsiella pneumoniae Bacterial isolates CRKP-1
8 μg/mL
MIC
PMID11085990;35052952 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11085990/
FIRST PREV 1 ... 7 8 9 10 11 NEXT LAST
Showing 5 records on this page · Page 9 of 11