Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC563H855N143O147S10

DescriptionStandard

        MEKTIFLHCYAEALLFNFQYLHGSPWSSSAILFVYSSALFRWYVCILTIWSNYSGSMLLLLLLLTHFSRSDSYICARKGGTCNLSPCPLYNRIEGTCYRGKAKCCIR
    

Molecular Weight12299.33 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)5.68

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.0531

GRAVY Index0.32

Hydrophobic Moment 0.52

Boman Index0.18

Instability Index38.18

Aliphatic Index 94.86

Aromaticity 0.1589

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4621.07

LogP -35.62

H-bond Donors 176.0

H-bond Acceptors 166.0

Rotatable Bonds 392.0

Heavy Atoms 863.0

Ring Count 26.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189019 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence