Peptide Database

Peptide NameDc1.2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC80H146N22O23

DescriptionStandard

        NLLKSALKTVNKLLAAS
    

Molecular Weight1784.15 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1622

GRAVY Index0.45

Hydrophobic Moment 0.70

Boman Index0.10

Instability Index8.36

Aliphatic Index 149.41

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 753.85

LogP -7.40

H-bond Donors 26.0

H-bond Acceptors 26.0

Rotatable Bonds 63.0

Heavy Atoms 125.0

Ring Count 0.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265634 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyPleurocidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus epidermidis

Activity64 μM

MethodMIC

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