Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2433H3848N628O685S17

DescriptionStandard

        MARGPDSARRWATLVVLATLGTAVTTTTNPGIVARVTQKGLDYACQQGVVTLQKELEKITIPTFSGSFKIKYLGKGQYCFSSMVIQGFSLPNSQIRPSPGEGLDLAIRDASINIRGKWKARKNFIKLSGKFDLSVEGISILAGLKLGYDPDSGHSTVTCSNCSSHINTVRIRISGSRLGWLIQLFHKRIESSLQNAMTSKICEVVTSTVSSKLQPYFETLPVTTKLDKVAGVDYSLVAPPRATTDNLDGLLKGEFFSLAHRSPPPFAPPPMAFPADHDRMVYLGISEYFFNTAGFVYQEAGALNLTLRDDMIPKESKFRLTTKFFGTLIPQVAKMFPDMQMQLFIWASLPPKLTVNASGLDLIFVLDTQAFAILPNSSLDPLFQLEMNLNLSVHLGAKSDRLIGELRLDKLLLELKHSDIGPFSVELLQSVMNYVMPTIVLPAINRKLQKGFPLPLPAYIELYNLVLQPYQDFLLFGADVHYS
    

Molecular Weight53401.48 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)8.18

Net Charge (pH 7.4) 7.38

Charge Density (pH 7.0) 0.0169

GRAVY Index0.07

Hydrophobic Moment 0.69

Boman Index0.12

Instability Index35.63

Aliphatic Index 99.52

Aromaticity 0.0932

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 43110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0196404 VERIFIED: NO

Provenance & Taxonomy

OrganismOdocoileus virginianus texanus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria