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MYP_127718
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Basic Information
Ctx(Ile21)-Ha-I9K (Ctx-Ha peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C109H173N29O26
Standard
Sequence
GWLDVAKKKGKAAFNVAKNFI
Physicochemical Analysis
2305.72 Da
10.18
3.76
3.55
0.1789
-0.10
0.58
0.06
6.03
83.81
0.1429
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
914.69
-6.08
31.0
30.0
79.0
164.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0191954 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
24.9
Hemolysis
PMID22519531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22519531/
RECORD: Rec_0209569 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Cryptococcus neoformans
31 μM
MIC
PMID22519531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22519531/
RECORD: Rec_0237550 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Cryptococcus neoformans
31
MIC
PMID22519531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22519531/
RECORD: Rec_0244408 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID22519531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22519531/
RECORD: Rec_0296263 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida parapsilosis
31 μM
MIC
PMID22519531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22519531/
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