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MYP_127698
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
19 amino acids
C89H133N23O28S3
Standard
Sequence
CKQSCSFGPFTFVCDGNTK
Physicochemical Analysis
2069.34 Da
7.95
0.73
0.48
0.0384
-0.19
0.27
0.03
80.03
15.26
0.1579
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
834.77
-11.31
31.0
32.0
65.0
143.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0071974 VERIFIED: NO
Provenance & Taxonomy
Streptomyces griseovertic [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2023/0416797 A1 Evidence URLhttps://patents.google.com/patent/US20230416797A1/en PatentUS 2023/0416797 A1
RECORD: Rec_0132892 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0184229 VERIFIED: YES
Provenance & Taxonomy
Streptoverticillium griseoverticillatum [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
The structure has been revised (Hayashi F et al., 1990). Methyllanthionine rings between residues 1 and18 as well as between residues 5 and 11; a lanthionine occurs between Cys14 and residue 4. In addition, addition of Lys19 to dehydralanine at position 6 forms a lysinoalanine bridge. The Asp residue at position 15 is hydroxylated. Duramycins and cinnamycin specifically binds to phosphatidylethanolamine, thereby indirectly inhibiting the activity of phospholipase A2. Updated 2/2017
Bio-Activity Profile
Antimicrobial
PaperAntibiotics against plant disease. IV. Activity of duramycin against selected microorganisms.
RECORD: Rec_0262051 VERIFIED: YES
Provenance & Taxonomy
Streptoverticillium griseoverticillatum [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 2272918 | PubMed PMID: 2125590 PMID2272918;2125590 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2272918/
RECORD: Rec_0334343 VERIFIED: YES
Provenance & Taxonomy
Streptoverticillium griseoverticillatum PA-48009 [Fungus]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID2272918 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2272918/
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