Peptide Database

Peptide NameColicin-E2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length130 amino acids

Chemical FormulaC670H1049N199O191S3

DescriptionStandard

        MLGAHRIHRPFAEDITGLWLEAAEKELGSPVPSQIADQLRGQKFESFDKFRESFWLTVSEDGNLLSQFASKNQRLIKKGRSPFALPQEHVGKRSRYEIHHVEEIQHGGKVYDVDNMRVMTPKSHINIHRK
    

Molecular Weight15043.91 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)3.22

Net Charge (pH 7.4) 2.56

Charge Density (pH 7.0) 0.0248

GRAVY Index-0.72

Hydrophobic Moment 0.72

Boman Index-0.13

Instability Index60.41

Aliphatic Index 75.00

Aromaticity 0.0846

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6316.24

LogP -60.04

H-bond Donors 218.0

H-bond Acceptors 205.0

Rotatable Bonds 510.0

Heavy Atoms 1063.0

Ring Count 27.0

Amide Bonds 140.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353817 VERIFIED: NO

Provenance & Taxonomy

OrganismVibrio spartinae [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal