Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC539H868N146O164S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNGGPTSIALTSCQTTSGDVDIKLNGKT
    

Molecular Weight12113.73 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)2.21

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index0.06

Hydrophobic Moment 0.54

Boman Index0.15

Instability Index18.60

Aliphatic Index 96.58

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4936.80

LogP -55.64

H-bond Donors 174.0

H-bond Acceptors 172.0

Rotatable Bonds 399.0

Heavy Atoms 852.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0251642 VERIFIED: NO

Provenance & Taxonomy

OrganismPloceus nigricollis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria