Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitor

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC31H46N8O13

DescriptionStandard

        DENSKF
    

Molecular Weight738.74 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.2062

GRAVY Index-2.07

Hydrophobic Moment 0.37

Boman Index-0.48

Instability Index8.33

Aliphatic Index 0.00

Aromaticity 0.1667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 372.76

LogP -4.60

H-bond Donors 12.0

H-bond Acceptors 12.0

Rotatable Bonds 25.0

Heavy Atoms 52.0

Ring Count 1.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027429 VERIFIED: YES

Provenance & Taxonomy

OrganismTerminalia chebula [Plant]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity100 μM

MethodIC50

RECORD: Rec_0261869 VERIFIED: YES