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MYP_127659
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Basic Information
Antimicrobial peptide 1 (ToAMP1; Cys-rich; Plant defensin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
38 amino acids
C187H292N48O57S7
Standard
Sequence
VAKCTEESGGKYFVFCCYKPTRICYMNEQKCESTCIGK
Physicochemical Analysis
4349.06 Da
8.29
1.68
1.36
0.0442
-0.36
0.36
-0.07
55.53
38.42
0.1316
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1720.45
-17.54
66.0
66.0
145.0
299.0
6.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0099198 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
A. niger
5.6 μM
MIC
PMID22640720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22640720/
RECORD: Rec_0116385 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
B. cinerea
5.8 μM
IC50
PaperDiscovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. flowers
RECORD: Rec_0164795 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0164998 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
X. campestris
PMID22640720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22640720/
RECORD: Rec_0206749 VERIFIED: YES
Provenance & Taxonomy
Taraxacum officinale [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
PMID22640720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22640720/
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