Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length481 amino acids

Chemical FormulaC2408H3777N635O667S13

DescriptionStandard

        MAARSLAAFGVVLAACLALTAATNPGFVVRITQAGLDYAHQHGITVLQKELAKLKLPDISGDFPVRHLGKVRYEISSLNLRSFHLPYSRISLVPNVGLQVAISNAFAEVDGNWRVKFHFIRDHGSFNLEVKNVYIKIDLKLGSDASGKPTVGTSACSTRISSVDVHFSGKFGWLYNLFYGAVESRFKKILESKVCDSVVRSVSGDLQHYLQTLPVTAKIDAKAGIDYSLVAPPMATAQTLDVDLKGEFFSLAHRGAVPFPPPVLALPPDHDRMVYFGASSYFFNTAGFAYHAAGALIFEITDSMIPKDVEFHLNTSTFAAFIPQLDKMYPNMLMKLRLSAPSAPFLSITPDGISLQPIVDIQAYAILPNTSLAHLFLLSLTGNVSATIDVKSGHIVGKLSVGRMKLSLKHSDVGTFQVRMLQSIMNIYASSILLPRVNERLAEGFPLPLPDRIQLSNILVQFHQNFLLLGADVHYTPRESR
    

Molecular Weight52711.45 Da

Isoelectric Point (pI)9.11

Net Charge (pH 7.0)7.98

Net Charge (pH 7.4) 6.76

Charge Density (pH 7.0) 0.0166

GRAVY Index0.20

Hydrophobic Moment 0.71

Boman Index0.16

Instability Index33.78

Aliphatic Index 103.20

Aromaticity 0.0956

Extinction Coeff. Reduced 33350.00

Extinction Coeff. Oxidized 33475.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346512 VERIFIED: NO

Provenance & Taxonomy

OrganismPhasianus colchicus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria