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MYP_127579
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Basic Information
Magainin-2 [F16W]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C116H181N31O29S
Standard
Sequence
GIGKFLHSAKKFGKAWVGEIMNS
Physicochemical Analysis
2505.93 Da
10.00
2.85
2.59
0.1237
-0.08
0.69
0.16
-3.80
72.17
0.1304
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
972.92
-7.41
34.0
34.0
86.0
177.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035856 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
40 μM
MIC
PMID9042968;9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0152233 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0180775 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
271 μM
Paperhttps://pubmed.ncbi.nlm.nih.gov/9335545/ PMID9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9335545/
RECORD: Rec_0199481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
80 μM
MIC
PMID9042968;9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0302000 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
80 μM
MIC
PMID9042968;9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
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