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MYP_127543
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Basic Information
PMAP-37
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C192H318N58O56
Standard
Sequence
GLLSRLRDFLSDRGRRLGEIIERIGQIIKDLSEFFQS
Physicochemical Analysis
4334.93 Da
8.74
0.77
0.56
0.0208
-0.27
0.94
-0.14
59.08
115.95
0.0811
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1899.24
-17.16
69.0
57.0
154.0
306.0
3.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0164356 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes CICC21533
62.5 μg/mL
MIC
PMID31437351 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31437351/
RECORD: Rec_0229800 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
0.025 μg/mL
MIC
PMID31437351 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31437351/
RECORD: Rec_0231413 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium SL1344
0.78 μg/mL
MIC
PMID31437351 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31437351/
RECORD: Rec_0283616 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
mouse red blood cells
1.95 μg/mL
Hemolysis
PMID31437351 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31437351/
RECORD: Rec_0307229 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Salmonella Typhimurium SL1344
0.78 μg/mL
MIC
PaperEnhancing the antibacterial activity of PMAP-37 by increasing its hydrophobicity.
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