Peptide Database

Peptide NameLysin (EC 3.5.1.28)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length486 amino acids

Chemical FormulaC2489H3771N685O735S13

DescriptionStandard

        MLTAIDYLTKKGWKISSDPRTYDGYPKNYGYRNYHENGINYDEFCGGYHRAFDVYSNETNDVPAVTSGTVIEANDYGNFGGTFVIRDANDNDWIYGHLQRGSMRFVVGDKVNQGDIIGLQGNSNYYDNPMSVHLHLQLRPKDAKKDEKSQVCSGLAMEKYDITNLNAKQDKSKNGSVKELKHIYSNHIKGNKITAPKPSIQGVVIHNDYGSMTPSQYLPWLYARENNGTHVNGWASVYANRNEVLWYHPTDYVEWHCGNQWANANLIGFEVCESYPGRISDKLFLENEEATLKVAADVMKSYGLPVNRNTVRLHNEFFGTSCPHRSWELHVGKGAPYTTANINRMKDYFIKRIKHYYDGGKLEVSKVAIIKQSDVKKEVKKQEAKQTVKTTDWKQNKDGIWYKTEHASFTVTASEGIITRYKGPWTGHPQAGVLQKGQTIKYDEVQKFDGHVWVSWKTFEGETVYMPVRTWDAKTGKVGPLWGTIK
    

Molecular Weight55466.56 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)9.05

Net Charge (pH 7.4) 7.67

Charge Density (pH 7.0) 0.0186

GRAVY Index-0.74

Hydrophobic Moment 0.67

Boman Index-0.06

Instability Index29.99

Aliphatic Index 65.95

Aromaticity 0.1214

Extinction Coeff. Reduced 128690.00

Extinction Coeff. Oxidized 128940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139169 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus phage phiSP119-1 [Virus]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Non-hemolytic Non-ribosomal