Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length142 amino acids

Chemical FormulaC698H1125N205O190S4

DescriptionStandard

        MNLPEASKPLARRFEGLRLKSYLCPAGVWTVGYGATGPDIGPGKVVTPEWAEDRLERDLMAFIPQVLKACPVLLTEPPDRLASILDFTFNLGGARLRASTLRTRVNARDWAGADHELRKWVRGGGRVLPGLVLRRAADAALL
    

Molecular Weight15556.92 Da

Isoelectric Point (pI)9.90

Net Charge (pH 7.0)5.59

Net Charge (pH 7.4) 5.27

Charge Density (pH 7.0) 0.0394

GRAVY Index-0.09

Hydrophobic Moment 0.93

Boman Index0.01

Instability Index33.22

Aliphatic Index 98.31

Aromaticity 0.0704

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6276.92

LogP -54.50

H-bond Donors 224.0

H-bond Acceptors 201.0

Rotatable Bonds 501.0

Heavy Atoms 1097.0

Ring Count 26.0

Amide Bonds 145.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0364286 VERIFIED: NO

Provenance & Taxonomy

Organismuncultured Caudovirales phage [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic