Peptide Database

Peptide NameGlucagon

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC153H219N41O52S2

DescriptionStandard

        HSEGTFSNDYSKYQEERMAQDFVQWLMNS
    

Molecular Weight3528.75 Da

Isoelectric Point (pI)4.50

Net Charge (pH 7.0)-3.15

Net Charge (pH 7.4) -3.41

Charge Density (pH 7.0) -0.1085

GRAVY Index-1.21

Hydrophobic Moment 0.70

Boman Index-0.18

Instability Index48.06

Aliphatic Index 26.90

Aromaticity 0.1724

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1554.07

LogP -17.26

H-bond Donors 53.0

H-bond Acceptors 52.0

Rotatable Bonds 117.0

Heavy Atoms 248.0

Ring Count 7.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374731 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

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