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MYP_127381
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Vif multimerization inhibitor
Standard
15 amino acids
C80H132N24O25
Standard
Sequence
SVTKLTEDRWNKPQK
Physicochemical Analysis
1830.05 Da
9.70
1.46
1.25
0.0974
-1.79
0.34
-0.50
88.68
45.33
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
839.15
-9.00
29.0
27.0
62.0
129.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0119102 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
RECORD: Rec_0124497 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:inhibit vif-vif binding
PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0231775 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1 Replication inhibition
HIV-1
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperPotent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins. | Yang B, Gao L, Li L, Lu Z, Fan X, Patel CA, Pomerantz RJ, DuBois GC, Zhang H. | J Biol Chem. 2003 Feb 21;278(8):6596-602. | DOI:10.1074/jbc.M210164200 | PMID:12480936 PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0287472 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Vif multimerization inhibitor
H9
10 %
Inhibition
PaperPotent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins. PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0297317 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/