Peptide Database

Peptide NameNeb-LFamide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC67H97N17O16

DescriptionStandard

        AYRKPPFNGSLF
    

Molecular Weight1396.59 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.79

Net Charge (pH 7.4) 1.60

Charge Density (pH 7.0) 0.1495

GRAVY Index-0.53

Hydrophobic Moment 0.22

Boman Index0.00

Instability Index8.37

Aliphatic Index 40.83

Aromaticity 0.2500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 537.31

LogP -3.87

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 40.0

Heavy Atoms 100.0

Ring Count 5.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177113 VERIFIED: YES

Provenance & Taxonomy

OrganismSarcophaga bullata [Animal]

FamilyNeb-LFamide

Tax ID7385

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0272667 VERIFIED: NO

Provenance & Taxonomy

OrganismNeobellieria bullata,Sarcophaga bullata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

TargetLocusta oviduct minimal

RECORD: Rec_0289530 VERIFIED: YES

Provenance & Taxonomy

OrganismSarcophaga bullata [Animal]

FamilyFMRFamide related peptide

Tax ID7385

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0312474 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/