Peptide Database

Peptide NameCycloviolacin O25

Function Ontology

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Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC118H189N33O38S6

DescriptionStandard

        CGESCVWIPCLTSAIGCSCKSSVCYRN
    

Molecular Weight2870.35 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.41

Charge Density (pH 7.0) 0.0260

GRAVY Index0.49

Hydrophobic Moment 0.32

Boman Index0.15

Instability Index44.04

Aliphatic Index 68.52

Aromaticity 0.0741

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1136.84

LogP -15.03

H-bond Donors 47.0

H-bond Acceptors 45.0

Rotatable Bonds 89.0

Heavy Atoms 195.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0132811 VERIFIED: YES

Provenance & Taxonomy

OrganismViola baoshanensis [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)