Peptide Database

Peptide NameAlpha-defensin 25 (Defensin-related cryptdin-25)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC444H719N129O142S10

DescriptionStandard

        MKTLVLLSALALLAFQVQADPIQNRDEESKIDEQPGKEDQAVSVSFGDPEGSSLQEECEDLICYCRTRGCKRRERLNGTCRKGHLMYMLWCC
    

Molecular Weight10456.89 Da

Isoelectric Point (pI)5.11

Net Charge (pH 7.0)-3.46

Net Charge (pH 7.4) -3.85

Charge Density (pH 7.0) -0.0376

GRAVY Index-0.46

Hydrophobic Moment 0.47

Boman Index-0.12

Instability Index53.54

Aliphatic Index 77.39

Aromaticity 0.0543

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4419.67

LogP -46.41

H-bond Donors 159.0

H-bond Acceptors 150.0

Rotatable Bonds 358.0

Heavy Atoms 725.0

Ring Count 10.0

Amide Bonds 99.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0090111 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic