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MYP_127359
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Basic Information
Oxt 4a
Annotation / Sequence feature ▸ Nuclear export signal
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
30 amino acids
C164H274N52O34S3
Standard
Sequence
GIRCPKSWKCKAFKQRVLKRLLAMLRQHAF
Physicochemical Analysis
3614.45 Da
11.59
8.82
8.53
0.2941
-0.32
0.83
-0.21
37.00
84.67
0.1000
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1427.01
-9.45
54.0
47.0
125.0
253.0
6.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0240344 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
1-11
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
10 μM
MIC
PaperNovel lynx spider toxin shares common molecular architecture with defense peptides from frog skin
RECORD: Rec_0278738 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0302047 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Oxt
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperFEBS J. 2011 Nov;278(22):4382-93. | http://www.ncbi.nlm.nih.gov/pubmed/21933345 PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
RECORD: Rec_0325280 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-10
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
RECORD: Rec_0327354 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-10
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
fluorescens and E
1 μM
MIC
PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
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