‹ ›
MYP_127359
← PREVIOUS NEXT → BACK
Basic Information
Oxt 4a
Annotation / Sequence feature ▸ Nuclear export signal
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
30 amino acids
C164H274N52O34S3
Standard
Sequence
GIRCPKSWKCKAFKQRVLKRLLAMLRQHAF
Physicochemical Analysis
3614.45 Da
11.59
8.82
8.53
0.2941
-0.32
0.83
-0.21
37.00
84.67
0.1000
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1427.01
-9.45
54.0
47.0
125.0
253.0
6.0
31.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0002263 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0004654 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-10
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
RECORD: Rec_0048279 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-10
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human erythrocytes
7 μM
EC50
PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
RECORD: Rec_0058958 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
1-11
Bio-Activity Profile
Antimicrobial
Pseudomonas fluorescens
1 μM
MIC
PaperNovel lynx spider toxin shares common molecular architecture with defense peptides from frog skin
RECORD: Rec_0103752 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
1-11
Bio-Activity Profile
Antimicrobial Toxicity
human erythrocytes as well
7 μM
EC50
PaperNovel lynx spider toxin shares common molecular architecture with defense peptides from frog skin
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4