Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length147 amino acids

Chemical FormulaC737H1162N202O224S11

DescriptionStandard

        MNLLLTFMICGLLTLVTKAGWNVERCWRYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL
    

Molecular Weight16789.04 Da

Isoelectric Point (pI)5.77

Net Charge (pH 7.0)-3.20

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0217

GRAVY Index-0.41

Hydrophobic Moment 0.69

Boman Index-0.03

Instability Index58.98

Aliphatic Index 79.59

Aromaticity 0.0748

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6841.23

LogP -68.05

H-bond Donors 241.0

H-bond Acceptors 236.0

Rotatable Bonds 547.0

Heavy Atoms 1174.0

Ring Count 28.0

Amide Bonds 159.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0117390 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence