Peptide Database

Peptide NameAntibacterial peptide PMAP-37

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length167 amino acids

Chemical FormulaC834H1355N237O252S6

DescriptionStandard

        METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTWRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEIQSVGLLSRLRDFLSDRGRRLGEKIERIGQKIKDLSEFFQS
    

Molecular Weight18926.51 Da

Isoelectric Point (pI)6.37

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.85

Charge Density (pH 7.0) -0.0031

GRAVY Index-0.39

Hydrophobic Moment 0.93

Boman Index-0.10

Instability Index38.93

Aliphatic Index 94.55

Aromaticity 0.0599

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7927.94

LogP -82.31

H-bond Donors 279.0

H-bond Acceptors 258.0

Rotatable Bonds 634.0

Heavy Atoms 1329.0

Ring Count 24.0

Amide Bonds 179.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187146 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence