Peptide Database

Peptide NameC12a

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC76H105N21O19

DescriptionStandard

        QKWEDWVRWIGN
    

Molecular Weight1616.78 Da

Isoelectric Point (pI)6.07

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0198

GRAVY Index-1.40

Hydrophobic Moment 0.65

Boman Index-0.16

Instability Index58.80

Aliphatic Index 56.67

Aromaticity 0.2500

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 679.49

LogP -2.89

H-bond Donors 24.0

H-bond Acceptors 19.0

Rotatable Bonds 50.0

Heavy Atoms 116.0

Ring Count 6.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0357477 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetFIV-M2(Feline immunodeficiency virus M2):inhibition of virus replication in MBM cells

Activity0.25 μg/mL

MethodIC50

RECORD: Rec_0365944 VERIFIED: YES