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MYP_127234
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Basic Information
ChaC11
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C129H199N31O38S7
Standard
Sequence
IPCGESCVWIPCISGMFGCSCKDKVCYS
Physicochemical Analysis
3016.60 Da
6.03
-0.30
-0.60
-0.0107
0.61
0.28
0.26
20.91
62.50
0.1071
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1075.02
-10.34
43.0
45.0
93.0
205.0
6.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0411309 VERIFIED: NO
Provenance & Taxonomy
Chassalia chartacea [Plant]
Structure & Mods
linear cystine-knot precursor topology [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Cytotoxic
RECORD: Rec_0420150 VERIFIED: YES
Provenance & Taxonomy
Chassalia chartacea [Plant]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
S-epidermis
>80 μM
MIC
PaperNovel Cyclotides and Uncyclotides with Highly Shortened Precursors from Chassalia chartacea and Effects of Methionine Oxidation on Bioactivities.
RECORD: Rec_0424624 VERIFIED: YES
Provenance & Taxonomy
Chassalia chartacea [Plant]
Cyclotide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defense peptide Cytolytic Cytotoxic Hemolytic
No Target Organism Found
PMID22467870 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467870/
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